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This Notch intracellular domain then translocates to the nucleus, where it forms a complex with CSL and Mastermind-like, regulating target gene expression and influencing critical cellular processes such as inflammation, apoptosis, and proliferation, which are crucial to the pathogenesis of PH as demonstrated by several clinical and preclinical studies (Fig

Int J Radiat Oncol Biol Phys 10(10):1975-85, 1984

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Nanoengineered glycan sensors enabling native glycoprofiling for medicinal applications: towards profiling glycoproteins without labeling or liberation steps

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