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When the cell becomes active, an electrical message reaches its end and signals these pockets to open

doi: 10.1007/s00404-012-2439-7 14 WangYLiNZengZTangLZhaoSZhouFet al

While preclinical models have yielded valuable insights into microglial heterogeneity, many markers defined in rodent systems [e.g., arginase 1 (Arg1) or rodent-specific chitinase-like protein (Ym1)] have limited expression or different regulation in human microglia

Enhancing Treg functione.g., via IL-2 administration or Treg adoptive transfermay mitigate inflammation and ferroptosis in COPD (122)

By addressing these critical insights, this review aims to advance the integration of polyphenols into functional foods, ensuring sustainability, efficacy, and broad accessibility in modern nutrition