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SOD plays an important role in antioxidant defenses, by converting superoxide into H 2 O 2 , which can then be further detoxified by other enzymes such as catalase.[182] There are three major classes of SOD, which are distinguished by the metal catalyst, which can be copper (Cu), Zn, Mn, iron, or nickel

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

10.3390/molecules27217604 5 Al AminM.DehbiaZ.NafadyM

GSH depletion (e.g., erastin treatment) or GRX5 silencing induces iron overload and ferroptosis, sensitizing cancer cells to chemotherapy (66)

Solvent A consisted of 94.9% (v/v) water, 5% (v/v) acetonitrile, and 0.1% (v/v) formic acid, and solvent B was composed of 5% (v/v) water, 94.9% (v/v) acetonitrile, and 0.1% (v/v) formic acid