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The therapies for MM have undergone great progress over the past years, including allogeneic hematopoietic stem cell transplantation (ASCT) and novel chemotherapies, such as proteasome inhibitors and immunomodulatory drugs 3

As denoted by the name, ferroptosis is an iron-dependent mechanism of cell death

5e,f) respectively

Further scrutiny of the locus revealed that both copy number, location and direction of individual GSTM1 genes are shuffled within the same locus (Fig