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Trends Pharmacol Sci 39:513524 Mandal PK, Dwivedi D, Joon S, Goel A, Ahasan Z, Maroon JC, Singh P, Saxena R, Roy RG (2023) Quantitation of brain and blood glutathione and Iron in healthy age groups using Biophysical and in vivo MR Spectroscopy: potential clinical application

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Consistent with these findings, HIF-1 and NRF2 expression levels are mutually associated, and high levels of these transcription factors correlate with poor outcomes in glioblastoma patients 90

Before CoQ 10 emerged as a ferroptosis suppressor, it was primarily viewed as an essential electron carrier in the mitochondrial electron transport chain (ETC), shuttling electrons from complexes I/II to complex III to maintain oxidative phosphorylation 18