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NAC was dosed at 200 or 300 mg/kg via intraperitoneal injection at 1 h after treatment with 600 mg/kg APAP

10.1111/j.1600-0757.2006.00157.x 121 PountosI.PanteliM.LampropoulosA.JonesE.CaloriG

13 Future directions Future advances in GSH-responsive nanomedicine should focus on clinically relevant development rather than proof of concept designs