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The metabolic profiling revealed that AOD9604 undergoes rapid proteolytic degradation in serum, generating a series of predictable fragment peptides

Oral dosing ranges discussed in research community use Phase Weeks 12 (start low) Daily dose 50 mg once daily Notes Morning dosing is the pattern most often reported

Additionally, inhibition of NNMT using MNAM resulted in a decline in performance during anaerobic endurance exercise in rats (Zhou et al., 2018)