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Chronic infection with often accompanied by intestinal bacterial overgrowth, may result in low serum B12 concentrations

This allows time for the body to respond to the injection and ensures any minor injection-site reactions have settled before travelling

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PhenoScanner V2 (31) was utilized to screen out the genetic instruments employed for vitamin B12 concentrations and associated with some phenotypes at the genome-wide significant level (Supplementary Table S2) for the horizontal pleiotropy concern