xpeptides bpc 157 BPC-157 – Research Peptide The peptide problem: Hype is

Clinical trials have shown that topical creams containing this peptide can produce noticeable changes in the skin's appearance

Innovent Biologics attached a fatty acid side chain to mazdutide to extend its half-life, allowing once-weekly dosing

Evidence of benefit in humans does not exist

This idea is supported by other neurodegenerative diseases experiencing severe localized copper deficiency, such as the motor neurons of ALS patients (Hilton et al., 2024), PD patients with up to 50% reduction of copper seen in the substantia nigra (Bisaglia and Bubacco, 2020), brain copper reductions in prion diseases (Sorenson, 2001), and notably Menkes disease which is characterized by an X-linked defect in copper transporting ATP7-A gene that leads to severe systemic copper deficiency and progressive neurodegeneration (Tmer and Mller, 2010)

Kuczewski N, Porcher C, Ferrand N, Fiorentino H, Pellegrino C, Kolarow R, Lessmann V, Medina I, Gaiarsa JL