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The particular vulnerability of DA neurons to inflammatory injury further highlights the central contribution of microglia-mediated inflammation to pparkinsons disease progression [167]

Briefly, rats were placed within a clear Plexiglas observation chamber on a hot plate analgesia meter

It is interesting to note that M1 and M2 macrophages also metabolize the amino acid arginine through two different pathways: M1via NOS into NO and citrulline and M2via arginase into ornithine and urea (Fig