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We incorporated analogs of the tryptophan (5-fluoro-tryptophan) and leucine (-cyclobutyl-alanine), and natural amino acid substitutions M7Y 39 and E5A 37 in RMG_14 40 , as these or similar substitutions had been previously described to improve binding affinity of peptides towards MDM2

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10.1093/oxfordjournals.eurheartj.a060425 148 TanaC.TicinesiA.PratiB.NouvenneA.MeschiT

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