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These findings indicate that omega-3 and vitamin B12 can counteract several PPA-induced biochemical abnormalities, although the evidence remains limited to an animal model and cannot be directly extrapolated to clinical populations ( The study of Doaei evaluated whether omega-3 supplementation modifies behavioral and social symptoms in children diagnosed with ASD according to DSM IV-TR criteria and ADOS assessment

Mice aged 1224 weeks and sex-matched were used for all experiments

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Nutrition 18:872879 Santamara A, Salvatierra-Snchez R, Vzquez-Romn B, Santiago-Lpez D, Villeda-Hernndez J, Galvn-Arzate S, Jimnez-Capdeville ME, Ali SF (2003) Protective effects of the antioxidant selenium on quinolinic acid-induced neurotoxicity in rats: In vitro and in vivo studies

Beyond DFX, newer compounds such as deferasirox, dauricine, and N -acetylcysteine offer alternative approaches by enhancing glutathione peroxidase 4 activity and replenishing antioxidant defenses 27