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Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity

In both HES lines, Grx1-roGFP2-HES2 and mito-Grx1-roGFP2-HES2, the sensor reacted in a concentration dependent manner to oxidation by H 2 O 2 with an increase in fluorescence ratio (R/R 0 ) under 405 nm excitation over 488 nm excitation (Figure 2E,F)

2019;20(20):5211.[DOI] 79

J Sci Food Agric 97:34873499 Fan W, Liu C, Cao B et al (2021) A meta-analysis of transcriptomic profiles reveals molecular pathways response to cadmium stress of gramineae