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These observations make it clear that care is needed in the frequent use of higher amounts of these supplements or other preparations of NS until more is known about the absorption, distribution, metabolism, and excretion of key constituents as well as their subsequent effects

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J Food Compos Anal 75:4960 Bremnes RM, Al-Shibli K, Donnem T et al (2011) The role of tumor-infiltrating immune cells and chronic inflammation at the tumor site on cancer development, progression, and prognosis: emphasis on non-small cell lung cancer