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Avram VF, Bna AM, Sima A, Aburel OM, Sturza A, Burlacu O, Timar RZ, Muntean DM, Elmr E, Creu OM (2021) Improvement of platelet respiration by cell-permeable succinate in diabetic patients treated with statins

hydrogen bond acceptors: 4 (lactone and hydroxyl oxygen)

A protocol followed reliably will outperform a theoretically optimal schedule that gets interrupted or forgotten

A typical FDA-approved regimen for pernicious anemia includes: 100 g IM/SC daily for 67 days Then every other day for 7 doses Then every 34 days for 23 weeks Followed by 100 g monthly for life Schedule follow-up and monitor progress Potassium levels should be monitored during the first 48 hours of treatment, as rapid red blood cell production may lead to hypokalemia and, rarely, sudden death

doi: 10.1016/j.foodchem.2020.128511 92