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2), with a strong relation with the principal antioxidant factor, the nuclear factor erythroid 2 (Nrf2) (Singh et al

Furthermore, epidemiological prospective studies have identified high plasma levels of IGF-1 as a potential risk factor for several malignancies (Hankinson et al, 1998)

Dillies, A

240 Similarly, HIF1 levels can increase under hypoxic conditions, modifying the expression of Hedgehog or Notch targets and altering responses to growth factors