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In the context of holistic support of personal health (particularly the de-medicalized evidence-based concept of lifestyle medicine) and based on consensus that food and physical exercise are considered medicines, the basic and simultaneously sound dual approach that forms the foundation to sustainable and lifelong health and wellbeing is Healthy Eating & Active Living. Based on the interwoven, related, and integrated nature from both the key pillars of health, (1) healthyat best WFPP, preferably vegetarian/vegandiets permanently linked to (2) regularat best daily and outdoors/in naturePA, sports, and exercise (1315, 155159, 161, 162, 165172) is the minimum recommendation to start tapping the full potential of the power of lifestyle to improve one's health on an individual level

10.1186/s13098-024-01346-4 31 ChenB.WenX.JiangH.WangJ.SongN.XieJ

-IV ALA was detected for up to 2 hours and up to 4 hours with oral ALA administration (Salehi, 2019)

Through experimental methods such as molecular docking, CESTA, and non-targeted metabolomics, we found that SAC can act on the Keap1/Nrf2/GPX4 signaling axis and regulate glutathione metabolism, effectively inhibiting ferroptosis and oxidative damage in colonic epithelial cells, thereby alleviating UC

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