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Busulfan, fludarabine, and cyclophosphamide (BFC) conditioning allowed stable engraftment after haplo-identical allogeneic stem cell transplantation in children with adrenoleukodystrophy and mucopolysaccharidosis

The challenge, therefore, is not to purify the recombinantly-derived protein, but to solubilize it and then fold it into native and biologically active protein [5]