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Specifically, HMMER allows us to identify protein sequences encoding functional domains through implementing probabilistic Hidden Markov Models (HMM) to search for protein sequence homologs against a profile database such as Pfam

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Zhao Y, Liu X, Liu X, Zhang J, Zhang Y, Wen Y, Yang G (2023) Salvianolic acid B exerts protective effects against A-induced neuroinflammation through the Inhibition of NLRP3 inflammasome activation and switching of M1/M2 polarization