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Yen-You Lins study showed that the diterpene compound excavatolide B from the gorgonian of Briareum excavatum produced potent anti-inflammatory activity in vitro and in vivo and inhibited the expression of iNOS and COX-2 mRNA

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rubellus contains an AMP called Lumbricin-1, which is rich in proline, [] and proposed as a natural defense against disease-causing microorganisms

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