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Additionally, MDSCs are capable of triggering Tregs' immunosuppressive effects by facilitating the secretion of IL-10 and IFN- [91]

Figures were created with UCSF Chimera and ChimeraX, developed by the Resource for Biocomputing, Visualization, and Informatics at the University of California, San Francisco, with support from National Institutes of Health R01-GM129325 and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases

However, the existing body of research suggests that DSIP could be a promising tool in the treatment of sleep disorders, chronic pain, and neurodegenerative diseases.

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Regardless of their differences, all of these disorders are associated with intellectual disability, motor abnormalities, and behavioral abnormalities