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[89] [94] [97] As an NMDA receptor antagonist, ketamine triggers a paradoxical acute burst of glutamate by selectively blocking inhibitory GABAergic neurons

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In mice treated with amoxicillin or ciprofloxacin, depletion of Lactobacillus reuteri (Firmicutes) led to reduced brain and serum GABA, downregulation of GABA-A receptors, and diminished 5-HT and DA, neurochemical changes that coincided with anxiety- and depression-like behaviors (Bibi et al., 2025)

In this study, AS mice were treated with different doses of sinomenine (10, 30, and 50 mg/kg), and in the sinomenine-treated AS mouse groups, the levels of TNF-, IL-1, and IL-6 were dose-dependently reduced

A Guide to Your Schedule How often you get B12 shots really comes down to your individual health picture