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Description

Our previous clinical tests successfully identified five valid biomarkers including proline, L-kynurenine, spermidine, taurine, and palmitoyl-L-carnitine, displaying high abundance in the plasma of 110 Chinese patients with lung cancer classified as adenocarcinomas ( n = 63), squamous carcinomas ( n = 41), and other histological types ( n = 6), as compared to healthy individuals 12

Mechanistically, Ipamorelin operates through the ghrelin receptor (GHS-R1a), coupling to Gq-mediated calcium mobilization and PKC activationa signaling pathway complementary to GHRH's cAMP-PKA mechanism