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Arch Phys Med Rehabil 91(11):16371640

falciparum in culture and against P

Each stage includes requirements that the FDA has found frequently deficient in warning letters, as indicated in Tables 1 and 2

Production of ROS from several sources initiate a cytotoxic cascade of events that culminate in cell death

Proposed Mechanism of Action In theory, the vaccine works by: Delivering mRNA instructions encoding tumour-related antigens Presenting these antigens to immune cells Activating cytotoxic T-cells Directing immune attack toward cancer cells Despite these theoretical mechanisms, several key questions remain unanswered: Which tumour antigens are targeted Which cancer types are included Whether immune activation leads to real tumour shrinkage How long the immune response lasts What side effects may occur