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(iv) optimal Se status (100 nm/l in cell culture) is critical for alternative macrophage activation, leading to attenuated expression of proinflammatory mediators (Reference Nelson, Lei and Prabhu57)

Deficiency of Vitamin B12 causes nuclear maturation and division and causes pernicious anaemia

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Unlike the self-polymerization approach, requiring high alkalinity and long reaction times, the enzymatic method achieves fast polymerization under mild conditions, which broadens its range of substrates and applications (Magalhes et al., 2022)

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