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however, a potential second start codon is present in exon 3, which might produce a shorter variant (Fig

In SURPASS-2, the rates of all reported GI side effectsincluding nausea, diarrhoea, vomiting, dyspepsia, decreased appetite, constipation and abdominal painoccurring with tirzepatide (4044.9%) were generally comparable to those seen with semaglutide (41.2%) [9]

The crucial point is the change in the nature of the product: from a by-product to a pure, safe substance that is independently assessed on the basis of its toxicological, microbiological, and chemical safety

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