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Expression of the fibroblast growth factor receptor in women with leiomyomas and abnormal uterine bleeding

The basic biochemistry is well-established: it is a real endogenous peptide, it genuinely binds copper, it declines with age, and it produces measurable effects on collagen synthesis, wound healing, and gene expression

Immunofluorescent analysis of ex vivo tumors after 30 days of treatment showed a significant decrease in F4/80 expression (Fig