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4E, Supplementary Fig

Notably, glycitin treatment induced activation of the Nrf2/HO-1 signaling pathway

The suggested dose can be repeated at 1-2 week intervals depending on the case and response of the animal.

So if you took B12 and felt worse, and your blood B12 is elevated, and you have a constellation of symptoms across multiple systems that's three signals pointing toward MCAS as worth ruling out