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In summary, the pro-inflammatory transcriptional profile observed in leukocytes from patients with moderate and severe COVID-19 was clearly attenuated by vitamin B12, with no adverse effects predicted from these results

Astrocytes generate H 2 O 2 and NO via mitochondrial respiration and enzymes such as MAO-B, diamine oxidase, NADPH oxidases, and inducible nitric oxide synthase (iNOS) [359364]

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Secondly, neo-vasculatures tend to lack some adhesion molecules for example vasculature cell adhesion molecule-1 (VCAM-1)