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We demonstrated that alogliptin can alleviate nephrotoxicity by modulating oxidative stress, inflammation, and apoptosis pathways

AK9 is an adenylate kinase predominantly expressed in the testis, which catalyzes the interconversion of two molecules of ADP into one molecule of ATP and one molecule of AMP (2 ADP 1 ATP + 1 AMP)

Curcumin has antioxidant properties, downregulates nuclear factor Kappa B (NF-B) to inhibit pro-inflammatory cytokines, and activates AMP-activated protein kinase (AMPK) to promote fatty acid oxidation (Safari et al., 2023)

Some studies showed the absence of positive effects on tumor progression and survival with a 3:1 ratio of fatty acids to carbohydrates in a KD regimen in glioblastoma mouse models but changed to positive when the ratio increased to 4:1 or 6:1 (117)

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