Agonists such as bradykinin promote NO release by inducing Thr495 dephosphorylation, allowing CaM to activate eNOS (Harris et al., 2001)
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41,93 While a formal diagnosis of histamine intolerance may be relatively uncommon, given the low-risk associated with eliminating high-histamine foods, someone whose rosacea has persisted despite other treatment strategies may find it worthwhile to try a low-histamine diet