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Tesamorelin has the strongest evidence and has been shown to reduce visceral fat by about 15% to 20% over 6 to 12 months in adults with HIV-associated lipodystrophy

doi: 10.1111/pce.12003 10 Clemente-MorenoM

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Furthermore, elevated levels of Hcy, a byproduct of methionine metabolism, are associated with cardiovascular diseases and neurodegenerative disorders