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Skipsey et al., 2011)

Despite increasing interest in herbal interventions for mood disorders, the existing clinical literature has largely evaluated general depressive symptoms without distinguishing among specific clinical subtypes of depression

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The antibody can also be joined to an internal region of the effector molecule, or conversely, the effector molecule can be joined to an internal location of the antibody, as long as the attachment does not interfere with the respective activities of the molecules