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COMC-6 (2-crotonyloxymethyl-2-cyclohexenone) is a potent antitumor agent against both murine and human tumors in culture and in tumor-bearing mice ( Diarylsulfonylureas are a class of antitumor agent with interesting therapeutic efficacy against a wide range of cancers (Howbert et al., 1990

It intercepts free radicals before they can damage the delicate protein complexes of the electron transport chain, which are responsible for generating ATP

Designed for consistent daily use

However, if the administered drug has a long half-life, blood levels may still be high when the patient awakes in the morning

Initial dosing is 50 mg to 100 mg, and the dose may be repeated in 2 hours (maximum 200 mg/24 hours)