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Preclinical Studies Cerebral Ischemia: PMID: 34201112 Brain Protein Expression Profile Confirms the Protective Effect of Semax in Cerebral Ischemia-Reperfusion (2021) PMID: 32580520 Novel Insights Into the Protective Properties of Semax at the Transcriptome Level (2020) PMID: 28255762 Semax Regulates Expression of Immune Response Genes During Ischemic Brain Injury (2017) PMID: 24661604 Semax Affects Expression of Genes Related to Immune and Vascular Systems in Focal Ischemia (2014) BDNF and Neurotrophin Studies: PMID: 16635254 Semax Binds Specifically and Increases BDNF Protein in Rat Basal Forebrain (2006) PMID: 19662538 Comparison of NGF and BDNF Gene Expression Under Semax Action (2010) PMID: 17353092 Neurotrophin Gene Expression in Rat Brain Under Semax Action (2007) Other Mechanisms: PMID: 40692165 Semax Targets Opioid Receptor for Functional Recovery After Spinal Cord Injury (2025) PMID: 25310602 Semax Has High Affinity for Copper(II) and Protective Ability Against Metal Toxicity (2015) PMID: 35080861 Semax Affects Copper-Induced A Aggregation in Alzheimers Models (2022)The Peptide Semax Affects the Expression of Genes Related to the Immune and Vascular Systems in Rat Brain Focal Ischemia: Genome-Wide Transcriptional Analysis

Healthy cognitive enhancement: Studies in healthy individuals demonstrate improved attention, memory, and information processing following Semax administration

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