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[1] These structures, defined as chiral, have the peculiar characteristic of lacking second-order symmetry elements, namely a plane of symmetry, a center of inversion, or a rotation-reflection axis

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Key for these questions are the proteomic approaches aiming to identify nuclear PTM occurring on redox-sensitive residues, and the structure biology techniques designed to visualize redox-based modifications on protein structure (Zaffagnini et al., 2016