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2024;25:9085, Gatterer H, Villafuerte FC, Ulrich S, Bhandari SS, Keyes LE, Burtscher M

The RCTs reviewed in the meta-analyses included in this work were routinely reported as having significant heterogeneity, low to moderate methodologies, and high risk of bias, including poor blinding of investigators and subjects, analytical methods, and poor control of confounding factors

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Thus, future research should focus on developing diagnostic models based on genetic variations to predict HAPE susceptibility as accurately as possible

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