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A fully biodegradable and self-electrified device for neuroregenerative medicine

L., Monserrat, M

doi:10.1016/j.ntt.2006.05.003 Islam Z, Amuzie CJ, Harkema JR, Pestka JJ

Our study enhances these findings by integrating advanced control methods, such as Pontryagins minimum principle and Riccati equations, to dynamically regulate macrophage activity and prevent fibrosis progression with greater precision

As summarized by Stier, Vos, and Kenley in 2013, the pre-specified primary endpoint for statistically significant weight change across the dose range and study duration was not met, while the compound's tolerability profile remained comparable to placebo