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For instance, the blood alcohol concentration can be used to modify the biochemistry of methanol and ethylene glycol

The trial proceeded without reported toxicity, and no lethal dose threshold (LD1) was ever established in subsequent safety testing meaning researchers administering the compound could not find a dose that caused death in even 1% of test subjects across the animal model safety work that preceded and followed the human study

Your care team can suggest a sensible cadence based on your plan and how you respond, and will keep your expectations grounded throughout

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Ask him what are the signs of toxicity - and I'm willing to bet you will hear a list of all the B12 deficiency symptoms that he chooses not to recognise as such, even if you mentioned them all 15 years ago to the first GP