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[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Merliss RR

There are two pathways that can facilitate this: (1) alanine is converted to pyruvate to synthesize glucose via the gluconeogenesis pathway in liver tissue or (2) alanine converted into pyruvate moves into the TCA cycle to be oxidized in other tissues

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Because the valence electrons on sulfur are farther from the nucleus and are less tightly held than those on oxygen (3 p electrons versus 2 p electrons), sulfur compounds are more nucleophilic than their oxygen analogs