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The Biochemical Journal, 191 , 110

These proteins are rich in amino acids, which are essential for maintaining the skins natural barrier and promoting a healthy complexion

When autophagy is impaired, increased p62 competes with the DLG motif for binding to the Keap1 DC pocket and inhibits the ubiquitination of Nrf2, causing Nrf2 stabilization and the increased expression of cytoprotective genes