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1 2D Structure 2 Identification 2.1 Computed Descriptors 2.1.1 IUPAC Name (2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide 2.1.2 InChI InChI=1S/C38H49N9O5/c1-38(2,41)37(52)47-32(21-28-22-42-23-43-28)36(51)46-31(20-25-15-16-26-12-6-7-13-27(26)18-25)35(50)45-30(19-24-10-4-3-5-11-24)34(49)44-29(33(40)48)14-8-9-17-39/h3-7,10-13,15-16,18,22-23,29-32H,8-9,14,17,19-21,39,41H2,1-2H3,(H2,40,48)(H,42,43)(H,44,49)(H,45,50)(H,46,51)(H,47,52)/t29-,30+,31+,32-/m0/s1 2.1.3 InChI Key NEHWBYHLYZGBNO-BVEPWEIPSA-N 2.1.4 Canonical SMILES CC(C)(C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC3=CC=CC=C3C=C2)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCCCN)C(=O)N)N 2.1.5 Isomeric SMILES CC(C)(C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@H](CC2=CC3=CC=CC=C3C=C2)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)N[C@@H](CCCCN)C(=O)N)N 2.2 Other Identifiers 2.2.1 UNII 2.3 Synonyms 2.3.1 MeSH Synonyms 1
The apparent K m and V max of the diphenolase reaction were 0.18 mM and 34 mole min 1 mg 1 , respectively (Table 1)
However, given that several studies in oysters have found increased methylation associated with higher levels of gene expression, it is possible that increased methylation in stressful conditions allows for higher expression of stress response genes
For patients with both MCAS and autoimmunity, flare-ups are often more severe, prolonged, and resistant to standard interventions
