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Comorbidities present in pillar pain patients included hypertension (48%), hypothyroidism (30%), rheumatoid arthritis (26%), diabetes mellitus (22%), fibromyalgia (9%), and vitamin deficiencies (9%), with no cases of chronic kidney disease in this sample

Vascular injury and circulation studies

Second, cell type and microenvironmental specificity are insufficiently addressed: most research centers on renal tubular epithelial cells, while the role of ferroptosis in other renal resident cells (e.g., podocytes and mesangial cells) or infiltrating immune cells (e.g., macrophages and neutrophils) during I/R injury is largely unexplored

Z.MazandaraniM.HoseiniA.et al

examined the effects of a dietary supplement called TOSLA with collagen, vitamin C, and hyaluronic acid (HA) on skin density, texture, and other parameters in a randomized, double-blind, placebo-controlled trial over 16 weeks in Slovenia [53]