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At high concentrations, QUE catalyzes the reduction of metal ions, generating ROS and causing oxidative damage to DNA and other cellular components (52)

Here, we used non-parametric testing that does not rely on data normality and that has been shown to limit the rate of false positives in neuroimaging studies 38

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Conclusions Neutrophils are subjected to redox stress during inflammation, either by endogenous ROS or by ROS from surrounding immune cells and host tissue

Results A total of 267 dysregulated metabolites were identified in patients with MMA, including 185 upregulated and 82 downregulated metabolites