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Accessed August 15, 2023

PPs also inhibited the activity of DNA methyltransferases, leading to significant changes in the methylation pattern of specific genes involved in various types of cancers (391)

In clinical studies, the combination of high-frequency ventilation and iNO resulted in the greatest improvement in oxygenation in PPHN associated with diffuse parenchymal lung disease, such as RDS, MAS and pneumonia, but had no benefit in idiopathic PPHN (61)