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In: Ulloa-Aguirre A, Tao Y-X, editors

Liu ZC, et al

In mixed parenchymal and biliary diseases, the ratios of mean GT to ALP were approximately equivalent

3.3 Soluble uric acids organ-specific effects on metabolic dysfunction 3.3.1 Soluble uric acid-induced endothelial dysfunction and cardiovascular remodeling ( Figure 3 ) Figure 3 Persistently elevated SUA in the heart can act as a damage-associated molecular pattern under pathological conditions, recognized by Toll-like receptors (such as TLR4) on the surface of cardiomyocytes and immune cells

2.6 Evaluation of intracellular oxidative stress levels by H 2 DCFDA oxidation assay Oxidative stress levels in lymphoblasts were evaluated through indirect measuring of 2,7-dichlorodihydrofluorescein diacetate (H 2 DCFDA) oxidation by flow cytometry, based on the assumption that DCF fluorescence is proportional to the concentration of reactive redox species present in the cytoplasm[56]