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NNMT has been explored as a target in obesity, insulin resistance, and age-related metabolic decline, supporting the rationale for translational research into body composition and performance contexts (Kannt & Pfenninger, Frontiers in Physiology )

However, the pills must be taken on an empty stomach in order to be properly absorbed, which can be a challenge for some people

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As sleep, recovery, and body composition improve on tesamorelin, patients naturally feel more motivated to eat well