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While Dihexa-specific desensitization kinetics haven't been thoroughly characterized in long-term studies, applying known c-Met receptor regulation patterns suggests daily dosing beyond 46 weeks without rest periods would likely produce diminishing returns

Cerebrospinal fluid and blood cytokines as biomarkers for multiple sclerosis: a systematic review and meta-analysis of 226 studies with 13,526 multiple sclerosis patients

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This targeted modulation allows beneficial aspects of inflammation to proceed while limiting chronic inflammation that impedes repair