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10.1007/s11033-022-07468-0 56 GiacosaA.MorazzoniP.BombardelliE.RivaA.Bianchi PorroG.RondanelliM

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Consistent with other reports regarding C-terminal truncations of its ortholog HNF4 61 , truncating the ligand-binding domain of NHR-49 altered its nucleocytoplasmic distribution, favoring a more pronounced nuclear localization under ad libitum feed conditions when compared to the full-length receptor (Fig