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Skeletal muscles of mdx mice demonstrate increased quantities of oxidative damage markers including the by-products of lipid peroxidation and carbonyls (Haycock, Mac, & Mantle, 1998

For example, formulations using extracts of Azadirachta indica and Moringa oleifera for ZnONPs showed over 85% inhibition of important enzymes involved in the digestion of glucose, which is comparable to that of common medications such as acarbose (260) ( Table 3 ), whereas the extract from Eysenhardtia polystachya increased the release of insulin via INS-1 pancreatic cells ( Table 2 )

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doi: 10.1016/j.bbrc.2013.02.038

Targeting CD38 improves metabolic fitness and memory in 5xFAD mice via modulation of pathogenic T H 17-mediated immunity To address the potential mechanistic relationship between CD38 and altered T cell immunometabolic functions, we used the 5xFAD transgenic mouse model of AD